Subtype-selective effect and molecular regulation of celastrol and triptolide at human nicotinic acetylcholine receptors - Moon, Myungmi; Pyeon, Minsu; Yang, Jaehui; Yun, Jeongyeon; Yeom, Hye Duck; Lee, Mee-Hyun; Lee, Gihyun; Lee, Junho H. (Chemico-biological interactions, 2025)
Keywords: Binding Sites; Celastrol; Diterpenes - chemistry; Diterpenes - metabolism; Diterpenes - pharmacology; Epoxy Compounds - chemistry; Epoxy Compounds - metabolism; Epoxy Compounds - pharmacology; Humans; Molecular Docking Simulation; Mutation; Nicotinic acetylcholine receptors; Pentacyclic Triterpenes; Phenanthrenes - chemistry; Phenanthrenes - metabolism; Phenanthrenes - pharmacology; Receptors, Nicotinic - chemistry; Receptors, Nicotinic - genetics; Receptors, Nicotinic - metabolism; Subtype-specific effect; Tripterygium - chemistry; Triptolide; Triterpenes - chemistry; Triterpenes - metabolism; Triterpenes - pharmacology; Celastrol; Triptolide; Nicotinic acetylcholine receptors; Subtype-specific effect