24-Hour Intraocular Pressure Control Obtained with Evening- versus Morning-Dosed Travoprost in Primary Open-Angle Glaucoma

• Published in: Ophthalmology (Rochester, Minn.) Vol. 113; no. 3; pp. 446 - 450
• Main Authors: Konstas, Anastasios G.P., Mikropoulos, Dimitrios, Kaltsos, Kostantinos, Jenkins, Jessica N., Stewart, William C.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.03.2006; Elsevier
• Subjects: Biological and medical sciences; Circadian Rhythm; Cloprostenol - administration & dosage; Cloprostenol - adverse effects; Cloprostenol - analogs & derivatives; Cloprostenol - therapeutic use; Conjunctiva - blood supply; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Eye - drug effects; Glaucoma and intraocular pressure; Glaucoma, Open-Angle - drug therapy; Glaucoma, Open-Angle - physiopathology; Humans; Hyperemia - chemically induced; Intraocular Pressure - drug effects; Medical sciences; Miscellaneous; Ophthalmology; Pruritus - chemically induced; Travoprost; Treatment Outcome; Eye disease; Ophthalmology; Open angle glaucoma; Comparative study; Primary; Intraocular pressure

To evaluate the quality of 24-hour intraocular pressure (IOP) control between morning- and evening-dosed travoprost in primary open-angle glaucoma patients. Prospective, crossover, double-masked comparison. After a 6-week medicine-free period, 33 patients were randomized to receive travoprost dosed...