Reducing Mortality in the Ageing Patient: Treatment of the Primary Tumour Is Not Necessary
Robot-assisted radical prostatectomy for older men remains an unproven intervention in terms of both cancer control and functional and voiding outcomes. We highlight some of the evidence against radical surgery for older men while acknowledging that this is the direction of travel.
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Published in | European urology focus Vol. 3; no. 4-5; pp. 328 - 329 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
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Elsevier B.V
01.10.2017
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Abstract | Robot-assisted radical prostatectomy for older men remains an unproven intervention in terms of both cancer control and functional and voiding outcomes. We highlight some of the evidence against radical surgery for older men while acknowledging that this is the direction of travel. |
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AbstractList | Robot-assisted radical prostatectomy for older men remains an unproven intervention in terms of both cancer control and functional and voiding outcomes. We highlight some of the evidence against radical surgery for older men while acknowledging that this is the direction of travel. |
Author | Brewster, Simon F. Hamdy, Freddie C. Lamb, Alastair D. |
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BackLink | https://www.ncbi.nlm.nih.gov/pubmed/29097093$$D View this record in MEDLINE/PubMed |
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Cites_doi | 10.1056/NEJMoa012794 10.1016/j.eururo.2006.04.002 10.1056/NEJMoa043739 10.1056/NEJMoa1606220 10.1016/j.eururo.2016.09.040 10.1200/JCO.1998.16.1.275 10.1016/j.eururo.2010.06.005 10.1056/NEJMoa1011967 10.1056/NEJMoa1311593 10.1001/jama.283.3.354 |
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Copyright | 2017 European Association of Urology Copyright © 2017 European Association of Urology. Published by Elsevier B.V. All rights reserved. |
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References | Johnston, Shaw, Lamb (bib0040) 2017; 71 Stanford, Feng, Hamilton (bib0045) 2000; 283 Life expectancy for countries. Wilson, Gilling, Williams (bib0060) 2006; 50 Bill-Axelson, Holmberg, Garmo (bib0025) 2014; 370 Keasler (bib0005) 1945 Accessed 23rd September 2017. Bill-Axelson, Holmberg, Ruutu (bib0015) 2005; 352 Ahyai, Gilling, Kaplan (bib0055) 2010; 58 Holmberg, Bill-Axelson, Helgesen (bib0020) 2002; 347 Hamdy, Donovan, Lane (bib0035) 2016; 375 Bill-Axelson, Holmberg, Ruutu (bib0010) 2011; 364 Talcott, Rieker, Clark (bib0050) 1998; 16 Holmberg (10.1016/j.euf.2017.10.008_bib0020) 2002; 347 10.1016/j.euf.2017.10.008_bib0030 Hamdy (10.1016/j.euf.2017.10.008_bib0035) 2016; 375 Stanford (10.1016/j.euf.2017.10.008_bib0045) 2000; 283 Ahyai (10.1016/j.euf.2017.10.008_bib0055) 2010; 58 Talcott (10.1016/j.euf.2017.10.008_bib0050) 1998; 16 Johnston (10.1016/j.euf.2017.10.008_bib0040) 2017; 71 Bill-Axelson (10.1016/j.euf.2017.10.008_bib0010) 2011; 364 Keasler (10.1016/j.euf.2017.10.008_bib0005) 1945 Bill-Axelson (10.1016/j.euf.2017.10.008_bib0015) 2005; 352 Bill-Axelson (10.1016/j.euf.2017.10.008_bib0025) 2014; 370 Wilson (10.1016/j.euf.2017.10.008_bib0060) 2006; 50 |
References_xml | – volume: 370 start-page: 932 year: 2014 end-page: 942 ident: bib0025 article-title: Radical prostatectomy or watchful waiting in early prostate cancer publication-title: N Engl J Med contributor: fullname: Garmo – year: 1945 ident: bib0005 article-title: Just because you can, doesn’t mean you should publication-title: Lest we forget: a memoir of the Philippine liberation campaign contributor: fullname: Keasler – volume: 375 start-page: 1415 year: 2016 end-page: 1424 ident: bib0035 article-title: 10-Year outcomes after monitoring, surgery, or radiotherapy for localized prostate cancer publication-title: N Engl J Med contributor: fullname: Lane – volume: 364 start-page: 1708 year: 2011 end-page: 1717 ident: bib0010 article-title: Radical prostatectomy versus watchful waiting in early prostate cancer publication-title: N Engl J Med contributor: fullname: Ruutu – volume: 283 start-page: 354 year: 2000 end-page: 360 ident: bib0045 article-title: Urinary and sexual function after radical prostatectomy for clinically localized prostate cancer: the prostate cancer outcomes study publication-title: JAMA contributor: fullname: Hamilton – volume: 352 start-page: 1977 year: 2005 end-page: 1984 ident: bib0015 article-title: Radical prostatectomy versus watchful waiting in early prostate cancer publication-title: N Engl J Med contributor: fullname: Ruutu – volume: 347 start-page: 781 year: 2002 end-page: 789 ident: bib0020 article-title: A randomized trial comparing radical prostatectomy with watchful waiting in early prostate cancer publication-title: N Engl J Med contributor: fullname: Helgesen – volume: 16 start-page: 275 year: 1998 end-page: 283 ident: bib0050 article-title: Patient-reported symptoms after primary therapy for early prostate cancer: results of a prospective cohort study publication-title: J Clin Oncol contributor: fullname: Clark – volume: 58 start-page: 384 year: 2010 end-page: 397 ident: bib0055 article-title: Meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic enlargement publication-title: Eur Urol contributor: fullname: Kaplan – volume: 71 start-page: 381 year: 2017 end-page: 388 ident: bib0040 article-title: Mortality among men with advanced prostate cancer excluded from the ProtecT trial publication-title: Eur Urol contributor: fullname: Lamb – volume: 50 start-page: 569 year: 2006 end-page: 573 ident: bib0060 article-title: A randomised trial comparing holmium laser enucleation versus transurethral resection in the treatment of prostates larger than 40 grams: results at 2 years publication-title: Eur Urol contributor: fullname: Williams – volume: 347 start-page: 781 year: 2002 ident: 10.1016/j.euf.2017.10.008_bib0020 article-title: A randomized trial comparing radical prostatectomy with watchful waiting in early prostate cancer publication-title: N Engl J Med doi: 10.1056/NEJMoa012794 contributor: fullname: Holmberg – volume: 50 start-page: 569 year: 2006 ident: 10.1016/j.euf.2017.10.008_bib0060 article-title: A randomised trial comparing holmium laser enucleation versus transurethral resection in the treatment of prostates larger than 40 grams: results at 2 years publication-title: Eur Urol doi: 10.1016/j.eururo.2006.04.002 contributor: fullname: Wilson – volume: 352 start-page: 1977 year: 2005 ident: 10.1016/j.euf.2017.10.008_bib0015 article-title: Radical prostatectomy versus watchful waiting in early prostate cancer publication-title: N Engl J Med doi: 10.1056/NEJMoa043739 contributor: fullname: Bill-Axelson – volume: 375 start-page: 1415 year: 2016 ident: 10.1016/j.euf.2017.10.008_bib0035 article-title: 10-Year outcomes after monitoring, surgery, or radiotherapy for localized prostate cancer publication-title: N Engl J Med doi: 10.1056/NEJMoa1606220 contributor: fullname: Hamdy – volume: 71 start-page: 381 year: 2017 ident: 10.1016/j.euf.2017.10.008_bib0040 article-title: Mortality among men with advanced prostate cancer excluded from the ProtecT trial publication-title: Eur Urol doi: 10.1016/j.eururo.2016.09.040 contributor: fullname: Johnston – volume: 16 start-page: 275 year: 1998 ident: 10.1016/j.euf.2017.10.008_bib0050 article-title: Patient-reported symptoms after primary therapy for early prostate cancer: results of a prospective cohort study publication-title: J Clin Oncol doi: 10.1200/JCO.1998.16.1.275 contributor: fullname: Talcott – volume: 58 start-page: 384 year: 2010 ident: 10.1016/j.euf.2017.10.008_bib0055 article-title: Meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic enlargement publication-title: Eur Urol doi: 10.1016/j.eururo.2010.06.005 contributor: fullname: Ahyai – volume: 364 start-page: 1708 year: 2011 ident: 10.1016/j.euf.2017.10.008_bib0010 article-title: Radical prostatectomy versus watchful waiting in early prostate cancer publication-title: N Engl J Med doi: 10.1056/NEJMoa1011967 contributor: fullname: Bill-Axelson – volume: 370 start-page: 932 year: 2014 ident: 10.1016/j.euf.2017.10.008_bib0025 article-title: Radical prostatectomy or watchful waiting in early prostate cancer publication-title: N Engl J Med doi: 10.1056/NEJMoa1311593 contributor: fullname: Bill-Axelson – ident: 10.1016/j.euf.2017.10.008_bib0030 – volume: 283 start-page: 354 year: 2000 ident: 10.1016/j.euf.2017.10.008_bib0045 article-title: Urinary and sexual function after radical prostatectomy for clinically localized prostate cancer: the prostate cancer outcomes study publication-title: JAMA doi: 10.1001/jama.283.3.354 contributor: fullname: Stanford – year: 1945 ident: 10.1016/j.euf.2017.10.008_bib0005 article-title: Just because you can, doesn’t mean you should contributor: fullname: Keasler |
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SubjectTerms | Aged, 80 and over Aging - physiology Clinical Decision-Making - ethics Humans Life Expectancy Lower Urinary Tract Symptoms - diagnosis Lower Urinary Tract Symptoms - therapy Male Monitoring, Physiologic - standards Monitoring, Physiologic - trends Mortality - trends Patient Outcome Assessment Patient Selection - ethics Prostate - pathology Prostate - surgery Prostatectomy - adverse effects Prostatectomy - mortality Prostatic Neoplasms - mortality Prostatic Neoplasms - pathology Prostatic Neoplasms - surgery Randomized Controlled Trials as Topic Transurethral Resection of Prostate - methods Urinary Incontinence - complications |
Title | Reducing Mortality in the Ageing Patient: Treatment of the Primary Tumour Is Not Necessary |
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