Analysis of Post-Liver Transplant Hepatitis C Virus Recurrence Using Serial Cluster of Differentiation Antibody Microarrays

• Published in: Transplantation Vol. 99; no. 9; p. e120
• Main Authors: Rahman, Wassim, Tu, Thomas, Budzinska, Magdalena, Huang, Pauline, Belov, Larissa, Chrisp, Jeremy S, Christopherson, Richard I, Warner, Fiona J, Bowden, D Scott, Thompson, Alexander J, Bowen, David G, Strasser, Simone I, Koorey, David, Sharland, Alexandra F, Yang, Jean Y H, McCaughan, Geoffrey W, Shackel, Nicholas A
• Format: Journal Article
• Language: English
• Published: United States 01.09.2015
• Subjects: Adult; Aged; Antigens, CD - blood; Biomarkers - blood; Cluster Analysis; End Stage Liver Disease - diagnosis; End Stage Liver Disease - surgery; End Stage Liver Disease - virology; Female; Hepacivirus - immunology; Hepatitis C - blood; Hepatitis C - complications; Hepatitis C - diagnosis; Hepatitis C - immunology; Humans; Leukocytes - immunology; Liver Cirrhosis - diagnosis; Liver Cirrhosis - immunology; Liver Cirrhosis - virology; Liver Transplantation - adverse effects; Male; Middle Aged; Predictive Value of Tests; Protein Array Analysis; Recurrence; Risk Factors; Severity of Illness Index; Time Factors; Treatment Outcome

Hepatitis C virus (HCV) reinfection of the liver allograft after transplantation is universal, with some individuals suffering severe disease recurrence. Predictive markers of recurrent disease severity are urgently needed. In this study, we used a cluster of differentiation (CD) microarray to predi...