UCHL1 acts as a prognostic factor and promotes cancer stemness in cervical squamous cell carcinoma

• Published in: Pathology, research and practice Vol. 247; p. 154574
• Main Authors: Jia, Qingge, Wang, Hongjie, Xiao, Xin, Sun, Yameng, Tan, Xiao, Chai, Jia, Yang, Yanru, Yin, Zhiyong, Li, Mingyang, Wang, Ke, Liu, Jin
• Format: Journal Article
• Language: English
• Published: Germany Elsevier GmbH 01.07.2023
• Subjects: Bone Neoplasms; Breast Neoplasms; Cancer stem cells; Carcinoma, Squamous Cell - pathology; Cell Line, Tumor; Cell Proliferation - genetics; CESC; Female; Humans; Migration; Prognosis; Sincalide - pharmacology; Sincalide - therapeutic use; Ubiquitin Thiolesterase; UCHL1; Uterine Cervical Neoplasms - pathology; UCHL1; Prognosis; Cancer stem cells; CESC; Migration

The incidence and death rate of cervical cancer rank fourth among female malignant tumors worldwide. A growing number of researches are devoted to exploring more effective treatment methods and cancer stem cells (CSCs) are thought to be a potential therapeutic target in cervical cancer. In our study...