Fate of microfilariae of Dirofilaria immitis following use of levamisole as a microfilaricide [dogs]

• Published in: Zeitschrift fuer Parasitenkunde Vol. 68; no. 1; p. 93
• Main Authors: Simpson, C F, Jackson, R F
• Format: Journal Article
• Language: English
• Published: Germany 01.01.1982
• Subjects: Animals; Cell Nucleus - ultrastructure; Dirofilaria immitis - drug effects; Dirofilaria immitis - ultrastructure; Dirofilariasis - drug therapy; Dirofilariasis - parasitology; Dirofilariasis - veterinary; Dog Diseases - drug therapy; Dog Diseases - parasitology; Dogs; Filarioidea - drug effects; Granuloma - parasitology; Levamisole - therapeutic use; Liver - parasitology; Microfilariae - drug effects; Phagocytosis; Vacuoles - ultrastructure

A pretreatment liver biopsy was secured from each of three dogs with Dirofilaria immitis microfilariae counts of 29,500, 24,700, and 76,700/ml blood, respectively. Post-treatment biopsies were obtained 30 h later following treatment with a single dose of levamisole and a reduction in microfilariae c...