Asiaticoside induces cell proliferation and collagen synthesis in human dermal fibroblasts

• Published in: Universa medicina Vol. 34; no. 2; pp. 96 - 103
• Main Authors: Yuliati, Linda, Mardliyati, Etik, Bramono, Kusmarinah, Freisleben, Hans Joachim
• Format: Journal Article
• Language: English
• Published: Faculty of Medicine Trisakti University 15.12.2015
• Subjects: asiaticoside; fibroblast; proliferation; retinoic acid; type i collagen; type iii collagen

Background Asiatiocoside, a saponin component isolated from Centella asiatica can improve wound healing by promoting the proliferation of human dermal fibroblasts (HDF) and synthesis of collagen. The skin-renewing cells and type I and III collagen synthesis decrease with aging, resulting in the redu...