Unprecedented 4,9‐Seco‐Oplopanane and Seven Drimane Sesquiterpenoids from the Chinese Liverwort Lejeunea flava (Sw.) Nees
An unprecedented 4,9‐seco‐oplopanane (1), two undescribed drimane epimers (2 and 3), and five known drimane sesquiterpenoids (4–8) were isolated from the Chinese liverwort Lejeunea flava (Sw.) Nees. The structures of the new sesquiterpenoids were determined using nuclear magnetic resonance spectrosc...
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| Published in | Chemistry & biodiversity Vol. 19; no. 9; pp. e202200559 - n/a |
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| Main Authors | , , , , , , , , , |
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| Language | English |
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| Abstract | An unprecedented 4,9‐seco‐oplopanane (1), two undescribed drimane epimers (2 and 3), and five known drimane sesquiterpenoids (4–8) were isolated from the Chinese liverwort Lejeunea flava (Sw.) Nees. The structures of the new sesquiterpenoids were determined using nuclear magnetic resonance spectroscopy, electronic circular dichroism calculations, and single‐crystal X‐ray diffraction measurements. The inhibitory capacity of the new compounds against nitric oxide production in lipopolysaccharide‐induced RAW 264.7 murine macrophages, along with the cytotoxicity of the new compounds against A549 and HepG‐2 human cancer cell lines, were discussed. |
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| AbstractList | An unprecedented 4,9-seco-oplopanane (1), two undescribed drimane epimers (2 and 3), and five known drimane sesquiterpenoids (4-8) were isolated from the Chinese liverwort Lejeunea flava (Sw.) Nees. The structures of the new sesquiterpenoids were determined using nuclear magnetic resonance spectroscopy, electronic circular dichroism calculations, and single-crystal X-ray diffraction measurements. The inhibitory capacity of the new compounds against nitric oxide production in lipopolysaccharide-induced RAW 264.7 murine macrophages, along with the cytotoxicity of the new compounds against A549 and HepG-2 human cancer cell lines, were discussed.An unprecedented 4,9-seco-oplopanane (1), two undescribed drimane epimers (2 and 3), and five known drimane sesquiterpenoids (4-8) were isolated from the Chinese liverwort Lejeunea flava (Sw.) Nees. The structures of the new sesquiterpenoids were determined using nuclear magnetic resonance spectroscopy, electronic circular dichroism calculations, and single-crystal X-ray diffraction measurements. The inhibitory capacity of the new compounds against nitric oxide production in lipopolysaccharide-induced RAW 264.7 murine macrophages, along with the cytotoxicity of the new compounds against A549 and HepG-2 human cancer cell lines, were discussed. An unprecedented 4,9‐seco‐oplopanane (1), two undescribed drimane epimers (2 and 3), and five known drimane sesquiterpenoids (4–8) were isolated from the Chinese liverwort Lejeunea flava (Sw.) Nees. The structures of the new sesquiterpenoids were determined using nuclear magnetic resonance spectroscopy, electronic circular dichroism calculations, and single‐crystal X‐ray diffraction measurements. The inhibitory capacity of the new compounds against nitric oxide production in lipopolysaccharide‐induced RAW 264.7 murine macrophages, along with the cytotoxicity of the new compounds against A549 and HepG‐2 human cancer cell lines, were discussed. An unprecedented 4,9‐ seco ‐oplopanane ( 1 ), two undescribed drimane epimers ( 2 and 3 ), and five known drimane sesquiterpenoids ( 4 – 8 ) were isolated from the Chinese liverwort Lejeunea flava (Sw.) Nees. The structures of the new sesquiterpenoids were determined using nuclear magnetic resonance spectroscopy, electronic circular dichroism calculations, and single‐crystal X‐ray diffraction measurements. The inhibitory capacity of the new compounds against nitric oxide production in lipopolysaccharide‐induced RAW 264.7 murine macrophages, along with the cytotoxicity of the new compounds against A549 and HepG‐2 human cancer cell lines, were discussed. |
| Author | Shen, Tao Qian, Li‐Lin Han, Jing‐Jing Zhang, Jiao‐Zhen Xu, Ze‐Jun Zhou, Jin‐Chuan Zhu, Ming‐Zhu Li, Yi Wang, Tian Lou, Hong‐Xiang |
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| Cites_doi | 10.1016/S0375-9601(98)00607-0 10.1139/v89-210 10.1107/S0108767307043930 10.1016/S0944-7113(97)80078-5 10.1039/C8RA08125E 10.1351/pac200779040557 10.1021/acs.orglett.8b02888 10.1016/j.phytochem.2018.06.013 10.1016/S0031-9422(97)00220-3 10.1186/s12906-016-1347-y 10.1016/S0040-4020(01)92443-3 10.1039/D1QO01891D 10.3390/molecules18022029 10.1016/0031-9422(89)80210-9 10.1021/acs.orglett.9b04270 10.1111/j.1095-8339.2003.00235.x 10.1016/j.phytochem.2012.04.012 10.1107/S0021889808042726 10.1039/p19860000701 10.1007/s11418-010-0423-8 10.1071/CH9890659 10.1021/np50088a011 10.1021/acs.jnatprod.1c00964 10.1007/s13659-016-0104-8 |
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| References | 1989; 42 2009; 42 1997; 46 2015; 143 2013; 91 2022; 85 1992; 55 2016; 16 1997; 4 2018; 20 2007; 79 1994; 62 1989; 28 2016; 11 2013; 18 2016; 6 2018; 8 2010; 64 2018; 154 2019; 22 1986; 44 2022; 7 1981; 37 1998; 247 2011; 67 2008; 64 e_1_2_8_24_1 e_1_2_8_25_1 e_1_2_8_26_1 e_1_2_8_3_1 e_1_2_8_2_1 e_1_2_8_5_1 e_1_2_8_4_1 e_1_2_8_7_1 e_1_2_8_6_1 e_1_2_8_9_1 e_1_2_8_8_1 e_1_2_8_20_1 e_1_2_8_23_1 e_1_2_8_1_1 e_1_2_8_17_1 e_1_2_8_18_1 e_1_2_8_19_1 Gradstein S. R. (e_1_2_8_22_1) 1994; 62 e_1_2_8_13_1 e_1_2_8_14_1 e_1_2_8_15_1 e_1_2_8_16_1 e_1_2_8_10_1 Nagashima F. (e_1_2_8_21_1) 2016; 11 e_1_2_8_11_1 e_1_2_8_12_1 |
| References_xml | – volume: 7 start-page: 1790 year: 2022 end-page: 1796 article-title: ‘Diels–Alder adducts of a labdane diterpenoid from the Chinese liverwort ’ publication-title: Org. Chem. Front. – volume: 8 start-page: 39091 year: 2018 end-page: 39097 article-title: ‘Cyperane and eudesmane-type sesquiterpenoids from Chinese liverwort and their anti-diabetic nephropathy potential’ publication-title: RSC Adv. – volume: 11 start-page: 153 year: 2016 end-page: 157 article-title: ‘Terpenoids, Flavonoids and Acetogenins from Some Malagasy Plants’ publication-title: Nat. Prod. Commun. – volume: 42 start-page: 339 year: 2009 end-page: 341 publication-title: J. Appl. Crystallogr. – volume: 154 start-page: 85 year: 2018 end-page: 93 article-title: ‘Clerodane diterpenoids from the Chinese liverwort and their anti-inflammatory activity’ publication-title: Phytochemistry – volume: 85 start-page: 205 year: 2022 end-page: 214 article-title: ‘Pinguisane Sesquiterpenoids from the Chinese Liverwort and Their Anti-Inflammatory Activity’ publication-title: J. Nat. Prod. – volume: 46 start-page: 145 year: 1997 end-page: 150 article-title: ‘Sesquiterpenoids from the three Japanese liverworts , and ’ publication-title: Phytochemistry – volume: 44 start-page: 701 year: 1986 end-page: 710 article-title: ‘Structures of -herbertane sesquiterpenoids displaying antifungal properties from the liverwort ’ publication-title: J. Chem. Soc.-Perkin Trans. – volume: 4 start-page: 261 year: 1997 end-page: 263 article-title: ‘Diplophyllolide: a cytotoxic sesquiterpene lactone from the liverworts and ’ publication-title: Phytomedicine – volume: 20 start-page: 6550 year: 2018 end-page: 6553 article-title: ‘Plagiochianins A, Two -2,3-seco-Aromadendrane Derivatives from the Liverwort Plagiochila duthiana’ publication-title: Org. Lett. – volume: 22 start-page: 510 year: 2019 end-page: 514 article-title: ‘Probing the Interconversion of Labdane Lactones from the Chinese Liverwort ’ publication-title: Org. Lett. – volume: 6 start-page: 211 year: 2016 end-page: 216 article-title: ‘Sesquiterpenoids from the Rhizomes of ’ publication-title: Nat. Prod. Bioprospect. – volume: 16 start-page: 360 year: 2016 article-title: ‘Screening of traditional Chinese medicines with therapeutic potential on chronic obstructive pulmonary disease through inhibiting oxidative stress and inflammatory response’ publication-title: BMC Complementary Altern. Med. – volume: 247 start-page: 303 year: 1998 end-page: 308 article-title: ‘Quantum-mechanical interpretation of time-dependent density-functional theory’ publication-title: Phys. Lett. A. – volume: 18 start-page: 2029 year: 2013 end-page: 2051 article-title: ‘Structural Requirements for the Antifungal Activities of Natural Drimane Sesquiterpenes and Analogs, Supported by Conformational and Electronic Studies’ publication-title: Molecules – volume: 37 start-page: 649 year: 1981 end-page: 653 article-title: ‘The structure and chemistry of pebrolide, desacetylpebrolide and 1-deoxypebrolide, sesquiterpene benzoates from penicillium brevicompactum’ publication-title: Tetrahedron – volume: 143 start-page: 391 year: 2015 end-page: 410 article-title: ‘A phylogenetic analysis of the genera of Lejeuneaceae (Hepaticae)’ publication-title: Bot. J. Linn. Soc. – volume: 64 start-page: 112 year: 2008 end-page: 122 article-title: ‘A short history of SHELX’ publication-title: Acta Crystallogr. Sect. A – volume: 62 start-page: 1 year: 1994 end-page: 216 article-title: ‘Lejeuneaceae: Ptychantheae, Brachiolejeuneae’ publication-title: Flora Neotropica – volume: 64 start-page: 417 year: 2010 end-page: 422 article-title: ‘Cytotoxic, radical scavenging and antimicrobial activities of sesquiterpenoids from the Tahitian liverwort (Brid.) Nees (Mastigophoraceae)’ publication-title: J. Nat. Med. – volume: 91 start-page: 52 year: 2013 end-page: 80 article-title: ‘Biologically active compounds from bryophytes’ publication-title: Phytochemistry – volume: 79 start-page: 557 year: 2007 end-page: 580 article-title: ‘Biologically active compounds from bryophytes’ publication-title: Pure Appl. Chem. – volume: 28 start-page: 1207 year: 1989 end-page: 1209 article-title: ‘An oplopane from Senecio mexicanus’ publication-title: Phytochemistry – volume: 67 start-page: 1371 year: 2011 end-page: 1380 article-title: ‘Metabolites of the fairy ring fungus, Marasmiusoreades. Part 2. Norsesquiterpenes, further sesquiterpenes, and agrocybin’ publication-title: Can. J. Chem. – volume: 55 start-page: 1454 year: 1992 end-page: 1461 article-title: ‘Drimane Sesquiterpene lactones From Peniophora polygonia’ publication-title: J. Nat. Prod. – volume: 42 start-page: 659 year: 1989 article-title: ‘Transoid Homoallylic Proton-Proton Coupling Constants’ publication-title: Aust. J. Chem. – ident: e_1_2_8_15_1 doi: 10.1016/S0375-9601(98)00607-0 – ident: e_1_2_8_20_1 doi: 10.1139/v89-210 – ident: e_1_2_8_24_1 doi: 10.1107/S0108767307043930 – ident: e_1_2_8_5_1 doi: 10.1016/S0944-7113(97)80078-5 – ident: e_1_2_8_4_1 doi: 10.1039/C8RA08125E – ident: e_1_2_8_2_1 doi: 10.1351/pac200779040557 – ident: e_1_2_8_11_1 doi: 10.1021/acs.orglett.8b02888 – volume: 11 start-page: 153 year: 2016 ident: e_1_2_8_21_1 article-title: ‘Terpenoids, Flavonoids and Acetogenins from Some Malagasy Plants’ publication-title: Nat. Prod. Commun. – ident: e_1_2_8_25_1 doi: 10.1016/j.phytochem.2018.06.013 – ident: e_1_2_8_9_1 doi: 10.1016/S0031-9422(97)00220-3 – ident: e_1_2_8_26_1 doi: 10.1186/s12906-016-1347-y – ident: e_1_2_8_16_1 doi: 10.1016/S0040-4020(01)92443-3 – ident: e_1_2_8_13_1 doi: 10.1039/D1QO01891D – ident: e_1_2_8_19_1 doi: 10.3390/molecules18022029 – ident: e_1_2_8_14_1 doi: 10.1016/0031-9422(89)80210-9 – ident: e_1_2_8_12_1 doi: 10.1021/acs.orglett.9b04270 – ident: e_1_2_8_8_1 doi: 10.1111/j.1095-8339.2003.00235.x – ident: e_1_2_8_1_1 doi: 10.1016/j.phytochem.2012.04.012 – volume: 62 start-page: 1 year: 1994 ident: e_1_2_8_22_1 article-title: ‘Lejeuneaceae: Ptychantheae, Brachiolejeuneae’ publication-title: Flora Neotropica – ident: e_1_2_8_23_1 doi: 10.1107/S0021889808042726 – ident: e_1_2_8_7_1 doi: 10.1039/p19860000701 – ident: e_1_2_8_6_1 doi: 10.1007/s11418-010-0423-8 – ident: e_1_2_8_18_1 doi: 10.1071/CH9890659 – ident: e_1_2_8_17_1 doi: 10.1021/np50088a011 – ident: e_1_2_8_3_1 doi: 10.1021/acs.jnatprod.1c00964 – ident: e_1_2_8_10_1 doi: 10.1007/s13659-016-0104-8 |
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| Snippet | An unprecedented 4,9‐seco‐oplopanane (1), two undescribed drimane epimers (2 and 3), and five known drimane sesquiterpenoids (4–8) were isolated from the... An unprecedented 4,9‐ seco ‐oplopanane ( 1 ), two undescribed drimane epimers ( 2 and 3 ), and five known drimane sesquiterpenoids ( 4 – 8 ) were isolated from... An unprecedented 4,9-seco-oplopanane (1), two undescribed drimane epimers (2 and 3), and five known drimane sesquiterpenoids (4-8) were isolated from the... |
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| SubjectTerms | anti-inflammatory activity Aquatic plants Circular dichroism Cytotoxicity Dichroism Lejeunea flava Lipopolysaccharides liverworts Macrophages Magnetic resonance spectroscopy Nitric oxide NMR NMR spectroscopy Nuclear magnetic resonance Sesquiterpenoids Toxicity Tumor cell lines |
| Title | Unprecedented 4,9‐Seco‐Oplopanane and Seven Drimane Sesquiterpenoids from the Chinese Liverwort Lejeunea flava (Sw.) Nees |
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