Evaluation of potential punishing effects of 2,5-dimethoxy-4-methylamphetamine (DOM) in rhesus monkeys responding under a choice procedure

• Published in: Behavioural pharmacology Vol. 35; no. 7; p. 378
• Main Author: Maguire, David R
• Format: Journal Article
• Language: English
• Published: England 01.10.2024
• Subjects: Animals; Choice Behavior - drug effects; Conditioning, Operant - drug effects; DOM 2,5-Dimethoxy-4-Methylamphetamine - pharmacology; Dose-Response Relationship, Drug; Female; Fentanyl - pharmacology; Histamine - pharmacology; Macaca mulatta; Male; Punishment; Reinforcement, Psychology; Serotonin 5-HT2 Receptor Agonists - pharmacology

There has been substantial and growing interest in the therapeutic utility of drugs acting at serotonin 2A subtype (5-HT 2A ) receptors, increasing the need for characterization of potential beneficial and adverse effects of such compounds. Although numerous studies have evaluated the possible rewar...