Higher 5-HT1A Receptor Binding Potential During a Major Depressive Episode Predicts Poor Treatment Response: Preliminary Data from a Naturalistic Study - Parsey, Ramin V; Olvet, Doreen M; Oquendo, Maria A; Huang, Yung-yu; Ogden, R Todd; Mann, J John (Neuropsychopharmacology (New York, N.Y.), 2006)
Keywords: Adult; Adult and adolescent clinical studies; Antidepressive Agents - pharmacology; Antidepressive Agents - therapeutic use; Biological and medical sciences; Depression; Depressive Disorder, Major - drug therapy; Depressive Disorder, Major - genetics; Depressive Disorder, Major - metabolism; Female; Follow-Up Studies; Humans; Linear Models; Male; Medical sciences; Middle Aged; Mood disorders; Piperazines - metabolism; Predictive Value of Tests; Protein Binding - drug effects; Protein Binding - physiology; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Pyridines - metabolism; Receptor, Serotonin, 5-HT1A - genetics; Receptor, Serotonin, 5-HT1A - metabolism; Treatment Outcome; Mood disorder; Study under natural conditions; SSRI; [11C]WAY-100635; 5-HT1A Serotonine receptor; Treatment; Depression; Predictive factor; positron emission tomography; PET; Selective serotonin reuptake inhibitor; Emission tomography