Characterization of a conditional mutant of Rous sarcoma virus with alterations in early and late functions of cell transformation

• Published in: Virology (New York, N.Y.) Vol. 67; no. 2; pp. 474 - 486
• Main Authors: Bookout, J.B., Sigel, M.M.
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.01.1975

Mutants were isolated from γ-irradiated stocks of Schmidt-Ruppin Rous sarcoma virus (SR-RSV-2). One isolate, MI-100, displayed unusual properties in its temperature sensitivity of cell-transforming capabilities. Focus formation, colony formation in soft agar, and increased [ 3H]deoxyglucose uptake b...