Role and Function of A2A and A3 Adenosine Receptors in Patients with Ankylosing Spondylitis, Psoriatic Arthritis and Rheumatoid Arthritis

• Published in: International journal of molecular sciences Vol. 18; no. 4; p. 697
• Main Authors: Ravani, Annalisa, Vincenzi, Fabrizio, Bortoluzzi, Alessandra, Padovan, Melissa, Pasquini, Silvia, Gessi, Stefania, Merighi, Stefania, Borea, Pier, Govoni, Marcello, Varani, Katia
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 24.03.2017; MDPI
• Subjects: Rheumatic diseases; Rheumatoid arthritis; Tumor necrosis factor-TNF

Rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) are chronic inflammatory rheumatic diseases that affect joints, causing debilitating pain and disability. Adenosine receptors (ARs) play a key role in the mechanism of inflammation, and the activation of A2A and A3A...