Fabrication and characterization of nifedipine loaded β-cyclodextrin nanosponges: An in vitro and in vivo evaluation

• Published in: Journal of drug delivery science and technology Vol. 41; pp. 344 - 350
• Main Authors: Shringirishi, Madhuri, Mahor, Alok, Gupta, Rishikesh, Prajapati, Sunil Kumar, Bansal, Kuldeep, Kesharwani, Prashant
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.10.2017
• Subjects: Anti-hypertensive; Diphenyl carbonate; Nanosponges; Nifedipine; β-Cyclodextrin; β-Cyclodextrin; Nanosponges; Anti-hypertensive; Diphenyl carbonate; Nifedipine

Cyclodextrin based nanosponges are gaining much consideration due to their aptitude to augment oral solubility of poorly water-soluble medications such as nifedipine. Here in the contemporary research, diphenyl carbonate was employed for crosslinking the cyclodextrin successfully. DLS studies confir...