Defining Clinical Course of Patients Evaluated for Pediatric Acute-Onset Neuropsychiatric Syndrome: Phenotypic Classification Based on 10 Years of Clinical Data

• Published in: Developmental neuroscience Vol. 47; no. 4; pp. 270 - 286
• Main Authors: Masterson, Erin E., Miles, Kate, Schlenk, Noelle, Manko, Cindy, Ma, Meiqian, Farhadian, Bahare, Chang, Kiki, Silverman, Melissa, Thienemann, Margo, Frankovich, Jennifer
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland 01.08.2025
• Subjects: Adolescent; Autoimmune Diseases; Child; Child, Preschool; Disease Progression; Female; Humans; Longitudinal Studies; Male; Obsessive-Compulsive Disorder - classification; Obsessive-Compulsive Disorder - diagnosis; Phenotype; Research Article; Pediatrics; Pediatric acute-onset neuropsychiatric syndrome; Clinical course; Epidemiology; Disease progression

Abstract Introduction: Establishing clear and standardized terminology regarding disease state and course is crucial for enhancing communication, research, and treatment decisions, particularly when there are no clearly identified biological markers, as in the case of pediatric acute-onset neuropsyc...