Modeling biological tissue growth: discrete to continuum representations

• Published in: Physical review. E, Statistical, nonlinear, and soft matter physics Vol. 88; no. 3; p. 032704
• Main Authors: Hywood, Jack D, Hackett-Jones, Emily J, Landman, Kerry A
• Format: Journal Article
• Language: English
• Published: United States 01.09.2013
• Subjects: Cell Division; Cell Proliferation; Models, Biological; Stochastic Processes; Time Factors

There is much interest in building deterministic continuum models from discrete agent-based models governed by local stochastic rules where an agent represents a biological cell. In developmental biology, cells are able to move and undergo cell division on and within growing tissues. A growing tissu...