Physiological Functions of Peroxisome Proliferator-Activated Receptor β

• Published in: Physiological reviews Vol. 94; no. 3; pp. 795 - 858
• Main Authors: Neels, Jaap G., Grimaldi, Paul A.
• Format: Journal Article
• Language: English
• Published: United States 01.07.2014
• Subjects: Animals; Cell Differentiation; Cell Proliferation; Humans; Inflammation - metabolism; Muscles - physiology; PPAR-beta - physiology

The peroxisome proliferator-activated receptors, PPARα, PPARβ, and PPARγ, are a family of transcription factors activated by a diversity of molecules including fatty acids and fatty acid metabolites. PPARs regulate the transcription of a large variety of genes implicated in metabolism, inflammation,...