Dynamics of perinuclear actin ring regulating nuclear morphology

• Published in: Applied mathematics and mechanics Vol. 45; no. 8; pp. 1415 - 1428
• Main Authors: Yang, Haoxiang, Sun, Houbo, Shen, Jinghao, Wu, Hao, Jiang, Hongyuan
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.08.2024; Springer Nature B.V; CAS Key Laboratory of Mechanical Behavior and Design of Materials,Department of Modern Mechanics,University of Science and Technology of China,Hefei 230026,China
• Edition: English ed.
• Subjects: Applications of Mathematics; Assembly; Classical Mechanics; Compressive properties; Depolymerization; Endothelial cells; Fluid- and Aerodynamics; In vivo methods and tests; Mathematical Modeling and Industrial Mathematics; Mathematics; Mathematics and Statistics; Morphology; Partial Differential Equations; Ring structures; Shear flow; Transient response; Q66; 92C42; 92C10; O39; 92C05; compressive stress; actin dynamics; nucleus; mechanical force; perinuclear actin ring

Cells are capable of sensing and responding to the extracellular mechanical microenvironment via the actin skeleton. In vivo, tissues are frequently subject to mechanical forces, such as the rapid and significant shear flow encountered by vascular endothelial cells. However, the investigations about...