[18F]Flutemetamol amyloid-beta PET imaging compared with [11C]PIB across the spectrum of Alzheimer’s disease

• Published in: European journal of nuclear medicine and molecular imaging Vol. 41; no. 2; pp. 290 - 300
• Main Authors: Hatashita, Shizuo, Yamasaki, Hidetomo, Suzuki, Yutaka, Tanaka, Kumiko, Wakebe, Daichi, Hayakawa, Hideki
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.02.2014; Springer Nature B.V
• Subjects: Adult; Alzheimer Disease - diagnostic imaging; Alzheimer's disease; Aniline Compounds; Benzothiazoles; Cardiology; Case-Control Studies; Female; Humans; Imaging; Male; Medical imaging; Medicine; Medicine & Public Health; Middle Aged; Nuclear Medicine; Oncology; Original Article; Orthopedics; Positron-Emission Tomography; Radiology; Radiopharmaceuticals; Alzheimer’s disease; PET; Amyloid imaging; Amyloid beta (Aβ)

Purpose The aim was to identify the amyloid beta (Aβ) deposition by positron emission tomography (PET) imaging with the 18 F-labeled Pittsburgh compound B (PIB) derivative [ 18 F]flutemetamol (FMM) across a spectrum of Alzheimer’s disease (AD) and to compare Aβ deposition between [ 18 F]FMM and [ 11...