Association of gastrointestinal stromal tumor and acute myeloid leukemia preceded by myelodysplastic syndrome with refractory anemia

• Published in: Tumori Vol. 95; no. 2; pp. 240 - 242
• Main Authors: Sonmez, Mehmet, Arslan, Mehmet, Cobanoglu, Umit, Kavgaci, Halil, Ozbas, Hasan Mucahit, Aydin, Fazil, Ovali, Ercument, Omay, Serdar Bedii
• Format: Journal Article
• Language: English
• Published: United States 01.03.2009
• Subjects: Aged; Anemia, Refractory - etiology; Anemia, Refractory - pathology; Biopsy; Bone Marrow - pathology; Female; Gastrointestinal Stromal Tumors - complications; Gastrointestinal Stromal Tumors - pathology; Humans; Leukemia, Myeloid, Acute - complications; Leukemia, Myeloid, Acute - pathology; Myelodysplastic Syndromes - complications; Myelodysplastic Syndromes - pathology

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. GISTs are believed to be related to mutational activation of receptor tyrosine kinases, KIT, or platelet-derived growth factor receptor-alpha. The coexistence of GISTs with other neoplasms h...