Repression of the Capacity to Produce Tumor Necrosis Factor Alpha in Candida albicans-Infected Mice and Reversal of the Repression by Oral Juzen-taiho-to Treatment

• Published in: Nihon Ishinkin Gakkai zasshi Vol. 38; no. 2; pp. 183 - 187
• Main Authors: Abe, Shigeru, Akagawa, Gen, Tansho, Shigeru, Ochi, Hisako, Osumi, Masako, Komatsu, Yasuhiro, Uchida, Katsuhisa, Yamaguchi, Hideyo
• Format: Journal Article
• Language: English
• Published: The Japanese Society for Medical Mycology 1997
• Subjects: Candida albicans; Juzen taiho-to; macrophage; OK432; TNF

The effects of the kampo medicine, Juzen-taiho-to (TJ-48) on the capacity to produce tumor necrosis factor α (TNF) of Candida albicans-infected mice was examined. ICR mice was challenged intravenously with Candida albicans and given TJ-48, which had been reported to prolong the life span of Candida-...