GMI, a fungal immunomodulatory protein from Ganoderma microsporum, induce apoptosis via β‐catenin suppression in lung cancer cells - Hsin, I‐Lun; Hsu, Jen‐Chieh; Wu, Wen‐Jun; Lu, Hsueh‐Ju; Wu, Ming‐Fang; Ko, Jiunn‐Liang (Environmental toxicology, 2018)
Keywords: Apoptosis; Apoptosis - drug effects; beta catenin; beta Catenin - antagonists & inhibitors; beta Catenin - metabolism; Cancer; Catenin; Cell Line, Tumor; Cell survival; Cell Survival - drug effects; cell viability; Cells; Down-Regulation; Epidermal growth factor receptors; fungal immunomodulatory protein; Fungal Proteins - pharmacology; Fungi; Ganoderma; Ganoderma - metabolism; Gene expression; Gene silencing; Genes; Glycogen Synthase Kinase 3 beta - metabolism; GMI; Humans; Immunologic Factors - pharmacology; Immunomodulation; Immunomodulators; Kinases; luciferase; Lung cancer; lung neoplasms; Lung Neoplasms - pathology; Lungs; messenger RNA; Microsporum; neoplasm cells; pro-apoptotic proteins; proteasome endopeptidase complex; Proteasomes; Proteins; Survivin; transcription (genetics); Transcription activation; transcriptional activation; β‐catenin; lung cancer; β-catenin; apoptosis; GMI; fungal immunomodulatory protein