The link between Wnt-related, stress-related, and circadian genes in the dermal fibroblasts of individuals with attention-deficit hyperactivity disorder

• Published in: Journal of Neural Transmission
• Main Authors: Palm, Denise, Smigielski, Lukasz, Uzoni, Adriana, Tucha, Oliver, Thome, Johannes, Grünblatt, Edna
• Format: Journal Article
• Language: English
• Published: Austria 21.07.2025
• Subjects: Circadian rhythms; ADHD; Wnt signaling; Clock genes; Gene expression; DKK1

Attention-deficit/hyperactivity disorder (ADHD) has been associated with circadian rhythm disturbances, altered stress responses, and, in neural stem cells from ADHD patients, aberrant Wnt signaling. However, little is known about how these molecular pathways interact. This study aimed to investigat...