HiFuse: Hierarchical multi-scale feature fusion network for medical image classification

• Published in: Biomedical signal processing and control Vol. 87; p. 105534
• Main Authors: Huo, Xiangzuo, Sun, Gang, Tian, Shengwei, Wang, Yan, Yu, Long, Long, Jun, Zhang, Wendong, Li, Aolun
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.01.2024
• Subjects: Feature fusion; Hybrid network; Medical image classification; Multi-scale feature; Swin-Transformer; Feature fusion; Hybrid network; Medical image classification; Swin-Transformer; Multi-scale feature
• DOI: 10.1016/j.bspc.2023.105534
• ISSN: 1746-8094

Effective fusion of global and local multi-scale features is crucial for medical image classification. Medical images have many noisy, scattered features, intra-class variations, and inter-class similarities. Many studies have shown that global and local features are helpful to reduce noise interference in medical images. It is difficult to capture the global features of images due to the fixed size of the receptive domain of the convolution kernel. Although the self-attention-based Transformer can model long-range dependencies, it has high computational complexity and lacks local inductive bias. In this paper, we propose a three-branch hierarchical multi-scale feature fusion network structure termed as HiFuse, which can fuse multi-scale global and local features without destroying the respective modeling, thus improving the classification accuracy of various medical images. There are two key characteristics: (i) a parallel hierarchical structure consisting of global and local feature blocks; (ii) an adaptive hierarchical feature fusion block (HFF block) and inverted residual multi-layer perceptron(IRMLP). The advantage of this network structure lies in that the resulting representation is semantically richer and the local features and global representations can be effectively extracted at different semantic scales. Our proposed model’s ACC and F1 values reached 85.85% and 75.32% on the ISIC2018 dataset, 86.12% and 86.13% on the Kvasir dataset, 76.88% and 76.31% on the Covid-19 dataset, 92.31% and 88.81% on the esophageal cancer pathology dataset. The HiFuse model performs the best compared to other advanced models. Our code is open source and available from https://github.com/huoxiangzuo/HiFuse. •Proposed a novel three-branch hierarchical multi-scale feature fusion network structure.•Design of global and local feature blocks with CNN and self-attention, and their fusion by HFF block.•Effective fusion of global and local multi-scale features is crucial for medical image classification.•Validated the performance with four medical image datasets.•This work can contribute to various downstream tasks in medical imagery.