Novel inhibitors of disulfide/methyl-ATP pump inhibit the proliferation of cancer cells: Analogs of methionine

• Published in: Medical hypotheses Vol. 158; p. 110743
• Main Author: Benavides, Maximo A.
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.01.2022
• Subjects: Cancer cells; Disulfide; l-Methionine; Methyl; P53; Pump; l-Methionine; Methyl; Pump; Cancer cells; Disulfide; P53

Target-based chemotherapies have rapidly become a conventional approach to cancer treatment. However, cell membranes can be impermeable to some treatment candidates that require cellular internalization. Our previous in vitro study described several critical findings on the utility of l-methionine i...