Dopamine D2/D3-receptor and transporter densities in nucleus accumbens and amygdala of type 1 and 2 alcoholics

• Published in: Molecular psychiatry Vol. 6; no. 3; pp. 261 - 267
• Main Authors: TUPALA, E, HALL, H, BERGSTRÖM, K, SÄRKIOJA, T, RÄSÄNEN, P, MANTERE, T, CALLAWAY, J, HILTUNEN, J, TIIHONEN, J
• Format: Journal Article
• Language: English
• Published: Basingstoke Nature Publishing Group 01.05.2001
• Subjects: Addictive behaviors; Adult and adolescent clinical studies; Alcoholics; Alcoholism; Amygdala; Animal memory; Animal training; Autoradiography; Biological and medical sciences; Carrier proteins; Dopamine; Dopamine D2 receptors; Dopamine D3 receptors; Dopamine receptors; Dopamine transporter; Genetic aspects; Medical sciences; Nucleus accumbens; Physiological aspects; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Radioisotopes; Risk factors; Finland; Human; Nucleus accumbens; Autoradiography; D2 Dopamine receptor; Amygdala; Pathophysiology; Alcoholism; Biological transport; Postmortem; Brain (vertebrata)

Alcohol acts through mechanisms involving the brain neurotransmitter dopamine (DA) with the nucleus accumbens as the key zone for mediating these effects. We evaluated the densities of DA D(2)/D(3) receptors and transporters in the nucleus accumbens and amygdala of post-mortem human brains by using...