Intraindividual Variation of Meiotic Recombination Parameters in Pig Spermatocytes: A Preliminary Study

Meiotic recombination parameters like crossover (CO) rate or synaptonemal complex (SC) length are known to vary strongly between individuals and between cells from the same individual. The origins of this variability remain elusive, and little is known about the variations that might occur between d...

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Bibliographic Details
Published inCytogenetic and genome research Vol. 154; no. 4; p. 229
Main Authors Mary, Nicolas, Ferchaud, Stéphane, Barasc, Harmonie, Calgaro, Anne, Bonnet, Nathalie, Ducos, Alain, Pinton, Alain
Format Journal Article
LanguageEnglish
Published Switzerland 01.01.2018
Subjects
Intraindividual variation
Synaptonemal complex
Meiotic recombination
Meiosis
MLH1
Pig
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Summary:Meiotic recombination parameters like crossover (CO) rate or synaptonemal complex (SC) length are known to vary strongly between individuals and between cells from the same individual. The origins of this variability remain elusive, and little is known about the variations that might occur between different samples and/or over time within the same individual. To document this question, pachytene cells from 3 boars of the Large White breed were analyzed twice, at a 1-year interval, using immunocytological techniques. CO rate, SC length, and MLH1 inter-foci distances varied significantly between the 3 individuals. CO rate and SC length differed significantly between the 2 sampling periods for 1 individual. However, no significant differences were observed between the 2 samples for CO distribution and inter-foci distances in the 3 boars studied.
ISSN:1424-859X
DOI:10.1159/000488789