Discovery and Validation of Novel microRNA Panel for Non-Invasive Prediction of Prostate Cancer

• Published in: Curēus (Palo Alto, CA) Vol. 16; no. 4; p. e58207
• Main Authors: Kumari, Shweta, Manoj, Anveshika, Rungta, Sumit, Kumar, Manoj, Prasad, Gautam, Kumar, Durgesh, Mahdi, Abbas A, Ahmad, Mohammad Kaleem
• Format: Journal Article
• Language: English
• Published: United States Springer Nature B.V 13.04.2024; Cureus
• Subjects: Antigens; Biomarkers; Cancer therapies; Cell cycle; Chemotherapy; Genes; Genetics; Hyperplasia; Medical diagnosis; MicroRNAs; Oncology; Patients; Polymerase chain reaction; Prostate cancer; Signal transduction; Urology; United States > US; Massachusetts; Japan; microrna; prostate cancer; non-invasive; panel mirna; castration-resistant prostate cancer; diagnostic biomarker

Early diagnosis remains a challenge for prostate cancer (PCa) due to molecular heterogeneity. The purpose of our study was to explore the diagnostic potential of microRNA (miRNA) in both tissue and serum that may aid in the precise and early clinical diagnosis of PCa. The miRNA expression pattern an...