Impact of opioid analgesics on survival in cancer patients receiving immune checkpoint inhibitors

• Published in: Supportive care in cancer Vol. 32; no. 7; p. 467
• Main Authors: Kavgaci, Gozde, Guven, Deniz Can, Kaygusuz, Yunus, Karaca, Ece, Dizdar, Omer, Kilickap, Saadettin, Aksoy, Sercan, Erman, Mustafa, Yalcin, Suayib
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.07.2024; Springer Nature B.V
• Subjects: Adult; Age groups; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid - administration & dosage; Analgesics, Opioid - therapeutic use; Cancer therapies; Female; Humans; Immune Checkpoint Inhibitors - therapeutic use; Kidney cancer; Liver cancer; Lung cancer; Male; Medical prognosis; Medicine; Medicine & Public Health; Mesothelioma; Metastasis; Middle Aged; Monoclonal antibodies; Narcotics; Neoplasms - drug therapy; Neoplasms - mortality; Nursing; Nursing Research; Oncology; Pain management; Pain Medicine; Patients; Progression-Free Survival; Rehabilitation Medicine; Retrospective Studies; Immune checkpoint inhibitors; Cancer pain management; Survival; Opioid analgesics

   Purpose This study aimed to assess the effects of concurrent opioid analgesic (OA) use with immune checkpoint inhibitors (ICIs) on progression-free survival (PFS) and overall survival (OS). Methods In this observational retrospective study, we included advanced cancer patients who received ICIs a...