Evaluating the Efficacy and Safety of Tirzepatide on Glycaemic and Non-glycaemic Outcomes in Diabetes: A Systematic Review of Meta-Analyses

• Published in: Curēus (Palo Alto, CA) Vol. 16; no. 3; p. e56939
• Main Authors: Kaore, Shilpa, B, Bhavya, Khasbage, Sameer, Atal, Shubham
• Format: Journal Article
• Language: English
• Published: United States Cureus Inc 26.03.2024; Cureus
• Subjects: Antidiabetics; Clinical trials; Diabetes; Endocrinology/Diabetes/Metabolism; Glucagon; Glucose; Insulin; Meta-analysis; Peptides; Systematic review; body weight; dual agonist; type 2 diabetes mellitus; incretins; glycaemic control; tirzepatide

Tirzepatide is a novel once-a-week dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, recently approved for type 2 diabetes mellitus (T2DM) and obesity. A systematic review of the literature published in multiple meta-analyses on Tirzepatide...