Cerebral Amyloidosis: Postmortem Detection with Human 7.0-T MR Imaging System

• Published in: Radiology Vol. 253; no. 3; pp. 788 - 796
• Main Authors: van Rooden, Sanneke, Maat-Schieman, Marion L. C., Nabuurs, Rob J. A., van der Weerd, Louise, van Duijn, Sara, van Duinen, Sjoerd G., Natté, Remco, van Buchem, Mark A., van der Grond, Jeroen
• Format: Journal Article
• Language: English
• Published: United States 01.12.2009
• Subjects: Cadaver; Cerebral Amyloid Angiopathy - etiology; Cerebral Amyloid Angiopathy - pathology; Cerebral Cortex - pathology; Humans; Image Processing, Computer-Assisted - methods; Immunohistochemistry; Magnetic Resonance Imaging - methods; Risk Factors; Sensitivity and Specificity

To explore the ability of whole-body 7.0-T magnetic resonance (MR) imaging to depict differences in aspects of the cerebral cortex of postmortem human brain specimens with cerebral amyloid beta deposition in connection with Alzheimer disease (AD), Down syndrome, or sporadic or hereditary cerebral am...