Hepatic phytotoxins in herbal medicines: A review of Africa's pyrrolizidine alkaloid-containing plants, their traditional uses, contamination pathways and associated health risks

• Published in: South African journal of botany Vol. 161; pp. 78 - 89
• Main Authors: Letsyo, Emmanuel, Dzikunoo, John, Dzah, Courage Sedem, Adams, Zeenatu Suglo, Asante-Donyinah, David
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.10.2023
• Subjects: Asteraceae; Ethnomedicinal uses; Hepatotoxicity; Herbal preparations; Honey; Phytomedicine; Honey; HVOD; LC-MS/MS; GISD; Herbal preparations; PAs; Ethnomedicinal uses; SOS; Asteraceae; PANOs; Hepatotoxicity; Phytomedicine

Incidences of human exposure to pyrrolizidine alkaloids (PAs) and their adverse effects have previously been reported in three African countries. In view of the increasing intake of herbal remedies over the years, we highlight Africa's tropical and subtropical PA-containing plants commonly used...