Prognostic value of body composition out of PSMA-PET/CT in prostate cancer patients undergoing PSMA-therapy

• Published in: European journal of nuclear medicine and molecular imaging
• Main Authors: Roll, Wolfgang, Plagwitz, Lucas, Ventura, David, Masthoff, Max, Backhaus, Clemens, Varghese, Julian, Rahbar, Kambiz, Schindler, Philipp
• Format: Journal Article
• Language: English
• Published: Germany 28.06.2025
• Subjects: PSMA-therapy; Body composition; PSMA-PET

This retrospective study aims to develop a deep learning-based approach to whole-body CT segmentation out of standard PSMA-PET-CT to assess body composition in metastatic castration resistant prostate cancer (mCRPC) patients prior to [ Lu]Lu-PSMA radioligand therapy (RLT). Our goal is to go beyond s...