Cutaneous and subcutaneous imaging on FDG-PET: benign and malignant findings

F-18 fluorodeoxyglucose positron emission tomography (F-18 FDG PET) has been shown to be useful in the evaluation of many tumors due to its high sensitivity and specificity. However, false-positive interpretations may occur from benign subcutaneous and cutaneous etiologies. At our institution we hav...

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Bibliographic Details
Published inClinical nuclear medicine Vol. 34; no. 10; p. 675
Main Authors Blumer, Steven L, Scalcione, Luke R, Ring, Bobbi N, Johnson, Ravi, Motroni, Betty, Katz, Douglas S, Yung, Elizabeth Y
Format Journal Article
LanguageEnglish
Published United States 01.10.2009
Subjects
Adult
Aged
Aged, 80 and over
Female
Fluorodeoxyglucose F18
Humans
Male
Middle Aged
Neoplasms - diagnostic imaging
Positron-Emission Tomography
Postoperative Care
Skin - diagnostic imaging
Tomography, X-Ray Computed
Whole Body Imaging
Wound Healing
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Summary:F-18 fluorodeoxyglucose positron emission tomography (F-18 FDG PET) has been shown to be useful in the evaluation of many tumors due to its high sensitivity and specificity. However, false-positive interpretations may occur from benign subcutaneous and cutaneous etiologies. At our institution we have encountered FDG-PET scans which demonstrated a variety of cutaneous and subcutaneous lesions including stomas, hernias, rhinophyma, dose infiltrations, physiologic muscle uptake, and tophaceous gout. Additionally, malignant cutaneous and subcutaneous malignant lesions may also demonstrate substantial F-18 FDG uptake on PET scans, including lymphoma, skin metastases, and melanoma. The purpose of this atlas article is to demonstrate and review key features of various cutaneous and subcutaneous lesions, both benign and malignant, which can result in hypermetabolism on FDG-PET or PET-CT scans.
ISSN:1536-0229
DOI:10.1097/RLU.0b013e3181b53845