Effects of virgin olive oil phenolic compounds on health: solid evidence or just another fiasco?
Current research suggests that virgin olive oil (VOO) phenolics are potent preventive and therapeutic agents against metabolic diseases associated with inflammation and oxidative stress. Evidence-based medicine requires these effects be proved in randomized controlled trials (RCT), which are then as...
Saved in:
Published in | Grasas y aceites (Sevilla) Vol. 72; no. 2; p. e404 |
---|---|
Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Consejo Superior de Investigaciones Científicas
03.06.2021
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Current research suggests that virgin olive oil (VOO) phenolics are potent preventive and therapeutic agents against metabolic diseases associated with inflammation and oxidative stress. Evidence-based medicine requires these effects be proved in randomized controlled trials (RCT), which are then assessed in meta-analyses, to ensure that the alleged health benefits really proceed in humans. The available evidence is limited to the ability of VOO phenolic compounds to protect lipoproteins from oxidation and to reduce systolic pressure in hypertensive individuals. No RCT assessing the effects of VOO phenolics on diabetes and neurodegenerative diseases have been performed, and those focused on osteoarthritis and cancer provided very scarce information. Therefore, RCT in extensive and diverse population groups, with different disorders and phenolic doses adjusted to usual VOO consumptions are necessary to achieve high quality scientific evidence before nutritional recommendations can be given to the general public. |
---|---|
AbstractList | Current research suggests that virgin olive oil (VOO) phenolics are potent preventive and therapeutic agents against metabolic diseases associated with inflammation and oxidative stress. Evidence-based medicine requires these effects be proved in randomized controlled trials (RCT), which are then assessed in meta-analyses, to ensure that the alleged health benefits really proceed in humans. The available evidence is limited to the ability of VOO phenolic compounds to protect lipoproteins from oxidation and to reduce systolic pressure in hypertensive individuals. No RCT assessing the effects of VOO phenolics on diabetes and neurodegenerative diseases have been performed, and those focused on osteoarthritis and cancer provided very scarce information. Therefore, RCT in extensive and diverse population groups, with different disorders and phenolic doses adjusted to usual VOO consumptions are necessary to achieve high quality scientific evidence before nutritional recommendations can be given to the general public. |
Author | Castellano, J.M. Perona, J.S. |
Author_xml | – sequence: 1 givenname: J.M. orcidid: 0000-0003-3051-3264 surname: Castellano fullname: Castellano, J.M. – sequence: 2 givenname: J.S. orcidid: 0000-0001-5919-993X surname: Perona fullname: Perona, J.S. |
BookMark | eNo9kE1PAjEURRuDiYCu_APdm8F-TTt1YwxBJSFxo-va6QeUDC1pBxL-vaMQVy_3vXfP4kzAKKboALjHaEZlIx_XJz1DBAuC8BUYY9k0FSOYjcAYISwqymR9AyalbBEiHCM8Bt8L753pC0weHkNehwhTF44OptDB_cbFIRlo0m6fDtEObxFunO76zRMsw8lCdwzWRTMUMtweSg91TP3GZeiDLiY934Jrr7vi7i5zCr5eF5_z92r18bacv6wqQ6Tsq5YLXTuOufWeIa2Z1tS3LSa0rikTXFtEvGuFFN7ZusW1R94yKxjlxFjv6BQsz1yb9Fbtc9jpfFJJB_W3SHmtdO6D6ZyiLUJcYKeJoQwZ1iAiiZdctII03NCB9XBmmZxKyc7_8zBSv6LVIFpdRNMfYwdzow |
CitedBy_id | crossref_primary_10_3390_foods12081667 crossref_primary_10_3390_molecules26185537 crossref_primary_10_1016_j_fbp_2022_05_003 |
ContentType | Journal Article |
DBID | AAYXX CITATION DOA |
DOI | 10.3989/gya.0217201 |
DatabaseName | CrossRef DOAJ Directory of Open Access Journals |
DatabaseTitle | CrossRef |
DatabaseTitleList | CrossRef |
Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website |
DeliveryMethod | fulltext_linktorsrc |
EISSN | 1988-4214 |
ExternalDocumentID | oai_doaj_org_article_3b00671ea2c340c480292f967b7286c3 10_3989_gya_0217201 |
GroupedDBID | 29I 2J8 2WC 53G 5GY A8Z AAYXX ABDBF ADBBV AENEX ALMA_UNASSIGNED_HOLDINGS B14 BCNDV CITATION DC1 DIK DU5 EBD ECGQY EFA ESTFP ESX FAEIB GROUPED_DOAJ GX1 HRC KQ8 OK1 R9V R9Y RNS TUS ~8M |
ID | FETCH-LOGICAL-c299t-b67a5e616dff40aa4aa3fbb123553476ad02feb797fed5b15f0fd4d74362cdfe3 |
IEDL.DBID | DOA |
ISSN | 0017-3495 |
IngestDate | Tue Oct 22 15:07:35 EDT 2024 Fri Aug 23 02:11:22 EDT 2024 |
IsDoiOpenAccess | true |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 2 |
Language | English |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c299t-b67a5e616dff40aa4aa3fbb123553476ad02feb797fed5b15f0fd4d74362cdfe3 |
ORCID | 0000-0001-5919-993X 0000-0003-3051-3264 |
OpenAccessLink | https://doaj.org/article/3b00671ea2c340c480292f967b7286c3 |
ParticipantIDs | doaj_primary_oai_doaj_org_article_3b00671ea2c340c480292f967b7286c3 crossref_primary_10_3989_gya_0217201 |
PublicationCentury | 2000 |
PublicationDate | 2021-06-03 |
PublicationDateYYYYMMDD | 2021-06-03 |
PublicationDate_xml | – month: 06 year: 2021 text: 2021-06-03 day: 03 |
PublicationDecade | 2020 |
PublicationTitle | Grasas y aceites (Sevilla) |
PublicationYear | 2021 |
Publisher | Consejo Superior de Investigaciones Científicas |
Publisher_xml | – name: Consejo Superior de Investigaciones Científicas |
References | ref0 ref2 ref1 |
References_xml | – ident: ref0 – ident: ref1 – ident: ref2 |
SSID | ssj0026101 ssib004721642 |
Score | 2.3080363 |
Snippet | Current research suggests that virgin olive oil (VOO) phenolics are potent preventive and therapeutic agents against metabolic diseases associated with... |
SourceID | doaj crossref |
SourceType | Open Website Aggregation Database |
StartPage | e404 |
SubjectTerms | Evidence Health Hydroxytyrosol Oleocanthal Phenolic Compounds Virgin Olive Oil |
Title | Effects of virgin olive oil phenolic compounds on health: solid evidence or just another fiasco? |
URI | https://doaj.org/article/3b00671ea2c340c480292f967b7286c3 |
Volume | 72 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1NS8QwEA2yJy-iqLh-kcNe66b5bL2IisuiKAgu7K0mTWapLK3sh-C_N2m6sjcvXnoooZSXITOvnXkPoUFqqLDcmcRYRROulUs0B5HYkjLwpNkKCNPIzy9yPOGPUzHdsvoKPWFRHjgCN2Tt38LUaVoyTkqeEZpTyKUyimayjDqfqdgiU20kBk0a_isk5WkCSTdnMvOcIE7qsTzLh7NvfdXaNHW-MJvctCXh3-aa0T7a64pEfBtf7gDtuPoQvUeh4SVuAH9Vi1lV42buzyrcVHMcOrWCwi8OLeLBKckvq3EccrzGPr4qi11nIIqbBf5YL1dY1-34FYZKL8vm5ghNRg9v9-Ok80dISp9EVomRSgsnU2kBONGaa83AmDD9KhhXUltCwRmVK3BWmFQAAcutrxkkLS04dox6dVO7E4Qd5UJzLkqiJCeQeRLHPOAOhHUqFa6PBhtkis8og1F4-hAALDyARQdgH90F1H6XBO3q9obf0aLb0eKvHT39j4ecoV0auk_C9xJ2jnqrxdpd-PJhZS7bSPHXp9fsB2LDwMU |
link.rule.ids | 315,786,790,870,2115,27955,27956 |
linkProvider | Directory of Open Access Journals |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Effects+of+virgin+olive+oil+phenolic+compounds+on+health%3A+solid+evidence+or+just+another+fiasco%3F&rft.jtitle=Grasas+y+aceites+%28Sevilla%29&rft.au=Castellano%2C+J.M.&rft.au=Perona%2C+J.S.&rft.date=2021-06-03&rft.issn=0017-3495&rft.eissn=1988-4214&rft.volume=72&rft.issue=2&rft.spage=e404&rft_id=info:doi/10.3989%2Fgya.0217201&rft.externalDBID=n%2Fa&rft.externalDocID=10_3989_gya_0217201 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0017-3495&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0017-3495&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0017-3495&client=summon |