Prevalence of sudden arrhythmic death syndrome-related genetic mutations in an Asian cohort of whole genome sequence

• Published in: Europace (London, England) Vol. 22; no. 8; pp. 1287 - 1297
• Main Authors: Huang, Pang-Shuo, Hsieh, Chia-Shan, Chang, Sheng-Nan, Chen, Jien-Jiun, Chiu, Fu-Chun, Wu, Cho-Kai, Hwang, Juey-Jen, Chuang, Eric Y, Tsai, Chia-Ti
• Format: Journal Article
• Language: English
• Published: England 01.08.2020
• Subjects: Background mutation; Incidental variant; Sudden arrhythmic death syndrome

Recently, the spectrum of background mutation in the genes implicated in sudden arrhythmic death syndrome (SADS), has been elucidated in the Caucasian populations. However, this information is largely unknown in the Asian populations. We assessed the background rare variants (minor allele frequency...