Time-delayed contrast-enhanced MRI improves detection of brain metastases and apparent treatment volumes

• Published in: Journal of neurosurgery Vol. 124; no. 2; p. 489
• Main Authors: Kushnirsky, Marina, Nguyen, Vinh, Katz, Joel S, Steinklein, Jared, Rosen, Lisa, Warshall, Craig, Schulder, Michael, Knisely, Jonathan P S
• Format: Journal Article
• Language: English
• Published: United States 01.02.2016
• Subjects: Adult; Brain Neoplasms - pathology; Brain Neoplasms - secondary; Brain Neoplasms - surgery; Contrast Media; Humans; Image Processing, Computer-Assisted; Linear Models; Magnetic Resonance Imaging - methods; Meglumine - analogs & derivatives; Observer Variation; Organometallic Compounds; Radiosurgery - methods; Treatment Outcome; brain metastases; BM = brain metastasis; delayed MRI; GRE = gradient echo; SRS = stereotactic radiosurgery; gadobenate dimeglumine; oncology

Contrast-enhanced MRI is the preeminent diagnostic test for brain metastasis (BM). Detection of BMs for stereotactic radiosurgery (SRS) planning may improve with a time delay following administration of a high-relaxivity agent for 1.5-T and 3-T imaging systems. Metastasis detection with time-delayed...