Limited Generalizability of Retrospective Single-Center Cohort Study in Comparison to Multicenter Cohort Study on Prognosis of Hepatocellular Carcinoma

• Published in: Journal of hepatocellular carcinoma Vol. 11; pp. 1235 - 1249
• Main Authors: Kim, Ye Rim, Chung, Sung Won, Kim, Min-Ju, Choi, Won-Mook, Choi, Jonggi, Lee, Danbi, Lee, Han Chu, Shim, Ju Hyun
• Format: Journal Article
• Language: English
• Published: New Zealand Dove 01.07.2024; Dove Medical Press
• Subjects: bclc; external validation; liver cancer; Original Research; retrospective cohort; uicc; external validation; liver cancer; UICC; retrospective cohort; BCLC

We aimed to evaluate the generalizability of retrospective single-center cohort studies on prognosis of hepatocellular carcinoma (HCC) by comparing overall survival (OS) after various treatments between a nationwide multicenter cohort and a single-center cohort of HCC patients. Patients newly diagno...