Causal relationship between novel antidiabetic drugs and ischemic stroke: a drug-targeted Mendelian randomization study

• Published in: Frontiers in cardiovascular medicine Vol. 11; p. 1449185
• Main Authors: Yu, Zongliang, Liu, Xinyi, Feng, Xue, Zhang, Xiaonan, Gao, Rui
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 24.09.2024
• Subjects: Cardiovascular Medicine; DPP-4 inhibitors; GLP-1 receptor agonists; ischemic stroke; Mendelian randomization analysis; novel antidiabetic agents; SGLT-2 inhibitors; Mendelian randomization analysis; SGLT-2 inhibitors; DPP-4 inhibitors; GLP-1 receptor agonists; ischemic stroke; novel antidiabetic agents

The escalating global economic burden of ischemic stroke poses a significant public health challenge amid global aging trends. The broad therapeutic efficacy of new antidiabetic drugs may offer new options in the prevention and treatment of ischemic stroke. Consistent conclusions regarding the relat...