Diagnostic and Prognostic Value of Hyperammonemia in Patients with Liver Cirrhosis, Hepatic Encephalopathy, and Sarcopenia (Experts’ Agreement)

• Published in: Rossiĭskiĭ zhurnal gastroėnterologii, gepatologii, koloproktologii Vol. 34; no. 1; pp. 85 - 100
• Main Authors: Nadinskaia, M. Yu, Maevskaya, M. V., Bakulin, I. G., Bessonova, E. N., Bueverov, A. O., Zharkova, M. S., Okovityi, S. V., Ostrovskaya, A. S., Gulyaeva, K. A., Ivashkin, V. T.
• Format: Journal Article
• Language: English
• Published: Gastro LLC 19.03.2024
• Subjects: ammonia measurement methods; bcaa; branched-chain amino acids; hepatic encephalopathy; hyperammonemia; hyperammonemia treatment; l-ornithine-l-aspartate; lactulose; lola; pico; rifaximin; sarcopenia

Introduction. In cirrhotic patients, hyperammonemia develops due to impaired ammonia detoxification and portosystemic blood shunting and is most commonly associated with hepatic encephalopathy and sarcopenia. Currently, there are questions regarding the diagnosis of hyperammonemia and the effect of...