Age Trends in the Level of Serum Testosterone and Other Hormones in Middle-Aged Men: Longitudinal Results from the Massachusetts Male Aging Study

• Published in: The journal of clinical endocrinology and metabolism Vol. 87; no. 2; pp. 589 - 598
• Main Authors: Feldman, Henry A., Longcope, Christopher, Derby, Carol A., Johannes, Catherine B., Araujo, Andre B., Coviello, Andrea D., Bremner, William J., McKinlay, John B.
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Oxford University Press 01.02.2002; Endocrine Society
• Subjects: Adult; Aged; Aging; Aging - blood; Androgens; Biological and medical sciences; Birth control; Cohort Studies; Cross-Sectional Studies; Dehydroepiandrosterone; Dehydroepiandrosterone sulfate; Dihydrotestosterone; Estrone; Globulins; Gonadotropins; Gynecology. Andrology. Obstetrics; Hormones; Hormones - blood; Humans; Hydrocortisone; Longitudinal Studies; Luteinizing hormone; Male; Medical sciences; Metabolic diseases; Middle age; Middle Aged; Obesity; Pituitary; Pituitary (anterior); Population studies; Random Allocation; Reference Values; Sex hormones; Statistical analysis; Sterility. Assisted procreation; Testosterone; Testosterone - blood; Testosterone - metabolism; Trends; United States > US; Massachusetts; Human; Hormone; Obesity; Statistical analysis; Cross section; Sample; Estimation; Nutrition disorder; Sex; Albumin; Male; Bioavailability; Hydrocortisone; Globulin; Testosterone; Estrone; Pituitary gland; Serum; Nutritional status

We used longitudinal data from the Massachusetts Male Aging Study, a large population-based random-sample cohort of men aged 40–70 yr at baseline, to establish normative age trends for serum level of T and related hormones in middle-aged men and to test whether general health status affected the age...