Modeling aerosol bolus inhalations in the human lung with the multiple path particle deposition model: Comparison with experimental data

• Published in: Journal of aerosol science Vol. 185; p. 106547
• Main Authors: Asgharian, B., Price, O., Borojeni, A.A.T., Kuprat, A.P., Colby, S., Singh, R.K., Corley, R.A., Darquenne, C.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.03.2025
• Subjects: Bolus inhalations; MPPD; Particle dispersion; Subject-specific predictions; MPPD; Particle dispersion; Subject-specific predictions; Bolus inhalations; particle dispersion; bolus inhalations; subject-specific predictions

Existing one-dimensional (1D) models of aerosol dosimetry often ignore mixing mechanisms of inhaled aerosols during their transport in the lung. This mixing or aerosol dispersion results from different physical mechanisms in different regions of the lung. It is a higher order effect, which cannot be...