Is disposable continuous positive airway pressure system effective for the management of acute hypercapnic respiratory failure?

Aim This study aimed to investigate the effectiveness of disposable continuous positive airway pressure (DCPAP) system in decreasing the partial pressure of carbon dioxide (P a CO 2 ) levels in patients with acute hypercapnic respiratory failure (AHRF). Material and methods This retrospective observ...

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Published inIrish journal of medical science Vol. 192; no. 4; pp. 1931 - 1937
Main Authors Cevik, Erdem, Dogan, Deniz, Gumus, Kursat, Can, Derya, Acar, Yahya A.
Format Journal Article
LanguageEnglish
Published Cham Springer International Publishing 01.08.2023
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Abstract Aim This study aimed to investigate the effectiveness of disposable continuous positive airway pressure (DCPAP) system in decreasing the partial pressure of carbon dioxide (P a CO 2 ) levels in patients with acute hypercapnic respiratory failure (AHRF). Material and methods This retrospective observational study included patients treated in the emergency department (ED) with respiratory distress and P a CO 2  > 45 mmHg. Patients were divided into two groups (DCPAP and non-DCPAP), depending on the treatment received to treat AHRF. The difference between the baseline P a CO 2 levels in the first blood gas obtained from patients at the time of admission and the follow-up blood gas after treatment. Then, the calculated P a CO 2 decrease was divided by the time elapsed to obtain the rate of decrease in PaCO 2 levels in mmHg/min. The statistical analyses were performed using SPSS version 18.0 software. A p value of < 0.05 was considered statistically significant. Results A total of 61 patients were included in the study, 31 patients in the DCPAP group and 30 patients in the non-DCPAP group. The mean age of the patients was 74.03 ± 10.04, and the male/female was 23/38. The study demonstrated a statistically significant difference between the DCPAP and non-DCPAP groups in terms of P a CO 2 decreasing rate, and it was found to be twice higher in the DCPAP group (0.11 ± 0.07 mmHg/min) than in the non-DCPAP group (0.05 ± 0.06 mmHg/min). Conclusion The study demonstrated that the treatment of AHRF patients with a DCPAP provides a faster decrease in P a CO 2 levels in hypercapnic patients compared to standard medical therapy alone.
AbstractList Aim This study aimed to investigate the effectiveness of disposable continuous positive airway pressure (DCPAP) system in decreasing the partial pressure of carbon dioxide (P a CO 2 ) levels in patients with acute hypercapnic respiratory failure (AHRF). Material and methods This retrospective observational study included patients treated in the emergency department (ED) with respiratory distress and P a CO 2  > 45 mmHg. Patients were divided into two groups (DCPAP and non-DCPAP), depending on the treatment received to treat AHRF. The difference between the baseline P a CO 2 levels in the first blood gas obtained from patients at the time of admission and the follow-up blood gas after treatment. Then, the calculated P a CO 2 decrease was divided by the time elapsed to obtain the rate of decrease in PaCO 2 levels in mmHg/min. The statistical analyses were performed using SPSS version 18.0 software. A p value of < 0.05 was considered statistically significant. Results A total of 61 patients were included in the study, 31 patients in the DCPAP group and 30 patients in the non-DCPAP group. The mean age of the patients was 74.03 ± 10.04, and the male/female was 23/38. The study demonstrated a statistically significant difference between the DCPAP and non-DCPAP groups in terms of P a CO 2 decreasing rate, and it was found to be twice higher in the DCPAP group (0.11 ± 0.07 mmHg/min) than in the non-DCPAP group (0.05 ± 0.06 mmHg/min). Conclusion The study demonstrated that the treatment of AHRF patients with a DCPAP provides a faster decrease in P a CO 2 levels in hypercapnic patients compared to standard medical therapy alone.
AIMThis study aimed to investigate the effectiveness of disposable continuous positive airway pressure (DCPAP) system in decreasing the partial pressure of carbon dioxide (PaCO2) levels in patients with acute hypercapnic respiratory failure (AHRF). MATERIAL AND METHODSThis retrospective observational study included patients treated in the emergency department (ED) with respiratory distress and PaCO2 > 45 mmHg. Patients were divided into two groups (DCPAP and non-DCPAP), depending on the treatment received to treat AHRF. The difference between the baseline PaCO2 levels in the first blood gas obtained from patients at the time of admission and the follow-up blood gas after treatment. Then, the calculated PaCO2 decrease was divided by the time elapsed to obtain the rate of decrease in PaCO2 levels in mmHg/min. The statistical analyses were performed using SPSS version 18.0 software. A p value of < 0.05 was considered statistically significant. RESULTSA total of 61 patients were included in the study, 31 patients in the DCPAP group and 30 patients in the non-DCPAP group. The mean age of the patients was 74.03 ± 10.04, and the male/female was 23/38. The study demonstrated a statistically significant difference between the DCPAP and non-DCPAP groups in terms of PaCO2 decreasing rate, and it was found to be twice higher in the DCPAP group (0.11 ± 0.07 mmHg/min) than in the non-DCPAP group (0.05 ± 0.06 mmHg/min). CONCLUSIONThe study demonstrated that the treatment of AHRF patients with a DCPAP provides a faster decrease in PaCO2 levels in hypercapnic patients compared to standard medical therapy alone.
This study aimed to investigate the effectiveness of disposable continuous positive airway pressure (DCPAP) system in decreasing the partial pressure of carbon dioxide (P CO ) levels in patients with acute hypercapnic respiratory failure (AHRF). This retrospective observational study included patients treated in the emergency department (ED) with respiratory distress and P CO  > 45 mmHg. Patients were divided into two groups (DCPAP and non-DCPAP), depending on the treatment received to treat AHRF. The difference between the baseline P CO levels in the first blood gas obtained from patients at the time of admission and the follow-up blood gas after treatment. Then, the calculated P CO decrease was divided by the time elapsed to obtain the rate of decrease in PaCO levels in mmHg/min. The statistical analyses were performed using SPSS version 18.0 software. A p value of < 0.05 was considered statistically significant. A total of 61 patients were included in the study, 31 patients in the DCPAP group and 30 patients in the non-DCPAP group. The mean age of the patients was 74.03 ± 10.04, and the male/female was 23/38. The study demonstrated a statistically significant difference between the DCPAP and non-DCPAP groups in terms of P CO decreasing rate, and it was found to be twice higher in the DCPAP group (0.11 ± 0.07 mmHg/min) than in the non-DCPAP group (0.05 ± 0.06 mmHg/min). The study demonstrated that the treatment of AHRF patients with a DCPAP provides a faster decrease in P CO levels in hypercapnic patients compared to standard medical therapy alone.
Author Dogan, Deniz
Cevik, Erdem
Gumus, Kursat
Can, Derya
Acar, Yahya A.
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2022. The Author(s), under exclusive licence to Royal Academy of Medicine in Ireland.
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Keywords Hypercapnia
Noninvasive ventilation
Dyspnea
Continuous positive airway pressure
Carbon dioxide
Language English
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Snippet Aim This study aimed to investigate the effectiveness of disposable continuous positive airway pressure (DCPAP) system in decreasing the partial pressure of...
This study aimed to investigate the effectiveness of disposable continuous positive airway pressure (DCPAP) system in decreasing the partial pressure of carbon...
AIMThis study aimed to investigate the effectiveness of disposable continuous positive airway pressure (DCPAP) system in decreasing the partial pressure of...
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SubjectTerms Family Medicine
General Practice
Internal Medicine
Medicine
Medicine & Public Health
Original Article
Title Is disposable continuous positive airway pressure system effective for the management of acute hypercapnic respiratory failure?
URI https://link.springer.com/article/10.1007/s11845-022-03189-2
https://www.ncbi.nlm.nih.gov/pubmed/36243821
https://search.proquest.com/docview/2725189613
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