Micro RNA 100 sensitizes luminal A breast cancer cells to paclitaxel treatment in part by targeting mTOR

• Published in: Oncotarget Vol. 7; no. 5; pp. 5702 - 5714
• Main Authors: Zhang, Baotong, Zhao, Ranran, He, Yuan, Fu, Xing, Fu, Liya, Zhu, Zhengmao, Fu, Li, Dong, Jin-Tang
• Format: Journal Article
• Language: English
• Published: Impact Journals LLC 02.02.2016
• Subjects: Research Paper

Luminal A breast cancer usually responds to hormonal therapies but does not benefit from chemotherapies, including microtubule-targeted paclitaxel. MicroRNAs could play a role in mediating this differential response. In this study, we examined the role of micro RNA 100 (miR-100) in the sensitivity o...