Oxygen Uptake Rate Controlling Strategy Balanced with Oxygen Supply for Improving Coenzyme Q10 Production by Rhodobacter sphaeroides

• Published in: Biotechnology and bioprocess engineering Vol. 25; no. 3; pp. 459 - 469
• Main Authors: Wang, Ze-Jian, Zhang, Xingzi, Wang, Ping, Sui, Zhiwei, Guo, Meijin, Zhang, Siliang, Zhuang, Yingping
• Format: Journal Article
• Language: English
• Published: Seoul The Korean Society for Biotechnology and Bioengineering 01.06.2020; Springer Nature B.V; 한국생물공학회
• Subjects: Alzheimer's disease; Ammonium; Ammonium sulfate; Biosynthesis; Biotechnology; Carbon; Chemistry; Chemistry and Materials Science; Coenzyme Q10; Fermentation; Fermenters; Glucose; Industrial and Production Engineering; Metabolism; Microorganisms; Mutagenesis; Oxygen; Oxygen consumption; Oxygen transfer; Oxygen uptake; Physiological effects; Physiology; Research Paper; Respiration; Rhodobacter sphaeroides; Statistical analysis; Strategy; Sulfates; Viscosity; 생물공학; oxygen supply; OUR controlling strategy; balance; coenzyme Q

The effects of different oxygen uptake rates (OUR) on the physiological metabolism of Rhodobacter sphaeroides were investigated systematically in 50 L fermenters due to the significant influence on industrial coenzyme Q10 production under oxygen supply limitation. Meanwhile, the seriously decreased...