Acute stroke: automatic perfusion lesion outlining using level sets

• Published in: Radiology Vol. 269; no. 2; pp. 404 - 412
• Main Authors: Mouridsen, Kim, Nagenthiraja, Kartheeban, Jónsdóttir, Kristjana Ýr, Ribe, Lars R, Neumann, Anders B, Hjort, Niels, Østergaard, Leif
• Format: Journal Article
• Language: English
• Published: United States 01.11.2013
• Subjects: Aged; Algorithms; Blood Flow Velocity; Contrast Media; Female; Humans; Magnetic Resonance Imaging - methods; Male; Middle Aged; Organometallic Compounds; Pattern Recognition, Automated; Phantoms, Imaging; Stroke - diagnosis

To develop a user-independent algorithm for the delineation of hypoperfused tissue on perfusion-weighted images and evaluate its performance relative to a standard threshold method in simulated data, as well as in acute stroke patients. The study was approved by the local ethics committee, and patie...