Coordination chemistry of ligands: Insights into the design of amyloid beta/tau-PET imaging probes and nanoparticles-based therapies for Alzheimer’s disease

• Published in: Coordination chemistry reviews Vol. 430; p. 213659
• Main Authors: Tamil Selvan, Subramanian, Ravichandar, Roopa, Kanta Ghosh, Krishna, Mohan, Anand, Mahalakshmi, Pachaiyappan, Gulyás, Balázs, Padmanabhan, Parasuraman
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.03.2021
• Subjects: Alzheimer’s disease; Coordination chemistry; PET ligands; Therapeutic nanoparticles; PET ligands; Therapeutic nanoparticles; Alzheimer’s disease; Coordination chemistry

[Display omitted] •Clinically approved Aβ-PET tracers for different neurodegenerative diseases.•Superior cognitive performance of Florbetapir and FDG in distinguishing AD from MCI.•Aβ tracers with low topographical distribution, association with clinical severity.•Studies on the association of subco...