Drug evaluation after marketing

• Published in: Annals of internal medicine Vol. 90; no. 2; p. 257
• Main Authors: Slone, D, Shapiro, S, Miettinen, O S, Finkle, W D, Stolley, P D
• Format: Journal Article
• Language: English
• Published: United States 01.02.1979
• Subjects: Drug and Narcotic Control; Drug Evaluation - standards; Drug-Related Side Effects and Adverse Reactions; Humans; Safety; Time Factors; United States; United States

After marketing, drugs should be evaluated for safety and for efficacy. Present national systems are inadequate for both tasks. Safety can be evaluated by means of nonexperimental research, whereas evaluation of efficacy in a variety of settings representing normal medical practice generally require...