Synthesis, in vitro α-amylase activity and molecular docking study of benzoxazole derivatives

• Published in: Chemical Data Collections Vol. 51; p. 101133
• Main Authors: Ullah, Hayat, Rahim, Fazal, Uddin, Imad, Khan, Misbah Ullah, Khan, Fahad, Hussain, Amjad, Hussain, Rafaqat, Khan, Shoaib
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.06.2024
• Subjects: Benzoxazole; Molecular docking study; Structure activity relationship; Synthesis; α-amylase; Molecular docking study; Structure activity relationship; Synthesis; α-amylase; Benzoxazole

In current study, an efficient and simple synthesis of phenyl-benzoxazoles derivatives (1–14) were carried out, upon cyclization of 2-aminophenol with substituted aldehyde. All synthesized derivatives were characterized through NMR and HREI-MS spectroscopic techniques. All derivatives showed from ex...