Manganese-mediated/-catalyzed oxidative carboazidation of acrylamides

• Published in: ORGANIC CHEMISTRY FRONTIERS Vol. 4; no. 8; pp. 1555 - 1560
• Main Authors: Zhao, Danwei, Kang, Kai, Wan, Wen, Jiang, Haizhen, Deng, Hongmei, Chen, Yunrong, Hao, Jian
• Format: Journal Article
• Language: English
• Published: CAMBRIDGE Royal Soc Chemistry 01.08.2017
• Subjects: Chemistry; Chemistry, Organic; Physical Sciences; Science & Technology; COPPER PHOTOREDOX CATALYST; ACTIVATED ALKENES; HYPERVALENT IODINE; C-H AZIDATION; BOND-FORMING REACTIONS; ASYMMETRIC EPOXIDATION; OLEFINS; SUPRAMOLECULAR CLICK CHEMISTRY; GRIGNARD-REAGENTS; ALKYL AZIDES

Manganese-mediated/-catalyzed oxidative carboazidation of acrylamides was developed for the synthesis of various azido oxindoles in 32% to 99% yields. tert-Butyl peroxybenzoate (TBPB) was used as an oxidant for the Mn-catalyzed method. And a Mn(II)/Mn(IV)/Mn(III) catalysis cycle via a stepwise or co...