Synthesis, in vitro α-glucosidase, urease activities and molecular docking study of benzoxazole bearing Schiff base derivatives

• Published in: Chemical Data Collections Vol. 46; p. 101054
• Main Authors: Ullah, Hayat, Uddin, Imad, Khan, Fahad, Hussain, Rafaqat, Khan, Shoaib
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.08.2023
• Subjects: Alpha glucosidase; Benzoxazole; Molecular docking; Schiff base; Synthesis; Urease; Schiff base; Alpha glucosidase; Urease; Synthesis; Molecular docking; Benzoxazole

We have synthesis seventeen benzoxazole bearing Schiff base derivatives (1-17), characterized through different spectroscopic techniques i.e., 1H-NMR, 13C-NMR and HREI-MS and were screened against alpha-glucosidase and urease enzymes. All derivatives showed good inhibitory potential with IC50 value...